DOI: https://doi.org/10.21897/rmvz.94

Effect of L-glutamine levels in piglets diets challenged with Escherichia coli lipopolysacharides

Arturo Pardo L, Angela Poveda P, Caio da Silva, Andréa dos Santos, Emerson Venâncio, Vânia Arantes, Eduardo Nogueira

Resumen


ABSTRACT

Objective. To evaluate the effect of different levels of L-glutamine on weaned and immunologically challenged piglets with Escherichia coli lipopolysaccharides (LPS) on performance parameters, serum cortisol and defense cells. Materials and methods. Four levels of L –glutamine were evaluated (0, 1.0, 1.5, 2.0%) as well as the addition, or no addition, of LPS (0.3μg). 96 piglets were used (48 castrated males and 48 females) of Agroceres x PenArlan lineage, with an initial age of 21 days and 6.06±0.852 kg live weight. An experimental design was used on randomized blocks in a factorial setting 4 x 2 (levels of L- glutamine with or without challenge). Results. Cubic effect was shown for daily weight gain of unchallenged animals, and was better with the addition of 0.41% L- glutamine. Feed conversion improved with increased levels of L -glutamine for challenged animals. In the evaluation of defense cells, there was interaction of leukocytes with the levels of L- glutamine and the immune challenge. Eosinophils and lymphocytes showed a quadratic effect for the levels of L –glutamine, with a maximum value of 1.30% and 0.5%, respectively. Conclusions. L -glutamine supplementation of up to 2% in the diet improves feed conversion and favors the immune serum of weaned piglets challenged with LPS of E. coli.


Palabras clave


Animal performance; immunity; leukocytes; stress

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Referencias


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