Diarrea viral bovina: patogénesis e inmunopatología

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Autores

Lang Rondón B

Resumen

La diarrea viral bovina (DVB) representa un problema de ámbito mundial que causa considerables pérdidas tanto en ganado de carne como lechero, afectándolo de diversas formas las cuales están supeditadas a la edad del animal, estado inmunológico y momento de la gestación en el que se produce la infección. La DVB es causada por un virus ARN, género Pestivirus, familia Flaviviridae, el cual ha sido clasificado en 2 biotipos (citopático y no citopático) según su comportamiento en células de cultivo y en 2 genotipos (I y II) basados en su secuencia genética. Dependiendo de las cepas infectantes se presenta un cuadro clínico particular variando en severidad desde una forma subclínica, pasando por la forma clínica e incluso produciendo la fatal enfermedad de las mucosas o causando efectos deletéreos sobre el feto. A pesar de que en nuestro medio ya existen estudios sobre esta entidad, la implementación de metodologías diagnósticas constituye una limitante para el manejo de la misma. La presente revisión se enfoca en la patogenia e inmunopatología de la DVB.

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Detalles del artículo

Referencias

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