Physical origins of the cytoplasm and the emergence of the genetic code

Orígenes físicos del citoplasma y la emergencia del código genético

The origin of life is tightly linked to the origin of the genetic code, no organism could be considered alive whether it lacks the capacity to transmit and execute chemical instructions necessary to replicate, vary, mutate and inherit their traits to future generations. In this review I board the problem of what conditions are known to be necessary to prime the origin of what is considered the building blocks of  the genetic code.

Moreover it is discussed the ancestral origin of the cytoplasm as the matrix that supports a proto genetic code that promotes replication within but also its own synthesis so it is multiplied and preserved. These features provide the focus topic of the origin of life not only with experimentally well supported chemical evidence of DNA/RNA synthesis ex vivo but also with the fundamental descriptions of the biological principles that could allow us to understand the evolution of and the emergence of the living.

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