GENOTYPING OF Plasmodium falciparum WITH Pfmsp1, Pfmsp2 AND Pfglurp IN THE SOUTH OF CÓRDOBA, COLOMBIA

GENOTYPING OF Plasmodium falciparum WITH Pfmsp1, Pfmsp2 AND Pfglurp IN THE SOUTH OF CÓRDOBA, COLOMBIA

Published 2017-08-30

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Yasnot Acosta, M. F., Quintero P, G. E., Velasco P, M. C., & Rodríguez R, V. C. (2017). GENOTYPING OF Plasmodium falciparum WITH Pfmsp1, Pfmsp2 AND Pfglurp IN THE SOUTH OF CÓRDOBA, COLOMBIA. Journal Advances in Health, 1(2), 58-63. https://doi.org/10.21897/25394622.3447
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https://doi.org/10.21897/25394622.3447
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María Fernanda Yasnot Acosta
Bacteriologist, M. Sc. in Biomedical Sciences, Ph. D. in Biomedical Sciences- immunology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its initials in Spanish).
Gustavo Enrique Quintero P
Veterinary, M. Sc. in Tropical Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its initials in Spanish). Universidad de Córdoba, Faculty of Health Science, Department of Bacteriology
María Camila Velasco P
Bacteriologist, M. Sc. in Tropical Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its initials in Spanish).Universidad de Córdoba, Faculty of Health Science, Department of Bacteriology
Virginia Consuelo Rodríguez R
Bacteriologist, M. Sc. in Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its initials in Spanish
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María Fernanda Yasnot Acosta,

Bacteriologist, M. Sc. in Biomedical Sciences, Ph. D. in Biomedical Sciences- immunology. Microbiological and Biomedical Research
Group of Córdoba, (GIMBIC, according to its initials in Spanish).

Gustavo Enrique Quintero P,

 Veterinary, M. Sc. in Tropical Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its
initials in Spanish). Universidad de Córdoba, Faculty of Health Science, Department of Bacteriology

María Camila Velasco P,

Bacteriologist, M. Sc. in Tropical Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its
initials in Spanish).Universidad de Córdoba, Faculty of Health Science, Department of Bacteriology

Virginia Consuelo Rodríguez R,

Bacteriologist, M. Sc. in Microbiology. Microbiological and Biomedical Research Group of Córdoba, (GIMBIC, according to its initials
in Spanish

Introduction. Plasmodium falciparum is a highly polymorphic parasite. This condition allows it to evade the immune response of the host, to disseminate drug resistance and to favor transmission. Objective. To know the polymorphism of Pfmsp-1, Pfmsp-2 and Pfglurp markers in patients with P. falciparum malaria in the endemic area of the state of CórdobaColombiaG. Materials and methods. Genomic DNA extraction and Nested polymerase chain reaction (Nested PCR) were used to genotype clinical strains of Plasmodium falciparum from the endemic area of the State of Córdoba, Colombia. Results. The most polymorphic allelic families were IC3D7 pertaining to Pfmsp2 and C-terminal repetitive region (R2) of GLURP, and the highest frequency is that of the MAD20 allele. Conclusion. This study shows that multiplicity of P. falciparum infection is low, reflecting a low malaria transmission intensity in the southern area of the State of Córdoba.

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